Therapeutic Vaccines: Steady Wins the Race
AIDS Treatment News Nov 05 09"Also of interest are personally tailored vaccine strategies, such as the one that made a splash earlier this month at AIDS Vaccine 2009, the annual meeting of the Global HIV Vaccine Enterprise, in Paris. AGS-004, being developed by North Carolina–based Argos, customizes immune system cells from each individual, using HIV fragments known as messenger RNA, to maximize an HIV-positive person’s immune response to the virus. To do this, dendritic cells are removed from the body and combined with mRNA taken from the same individual’s HIV. The data presented at the Paris conference showed that the vaccine, when given just before an ARV treatment interruption, kept viral loads at least 1 log—more than an 80 percent reduction—below pre-ARV therapy levels in 13 of 16 patients. Full story...
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Low bone mineral density common in HIV-positive men
AIDS Treatment News 3 days ago"A large proportion of HIV-positive men have low bone mineral density, Australian researchers report in the December 1st edition of the Journal of Infectious Diseases.
Routine Screening for Depression: Identifying a Challenge for Successful HIV Care
AIDS Treatment News 3 days ago"Given the association between depressive symptomatology and poor rates of HIV viral suppression, screening and appropriate interventions for depressive symptoms are warranted in the HIV outpatient setting to improve outcomes.
The Needle Nexus
AIDS Treatment News 3 days ago"Needle exchange is AIDS prevention that works. While no one wants to have to put on a condom, every drug user prefers injecting with a clean needle.
Pregnancy, not nevirapine cause of liver toxicities in HIV-positive women
AIDS Treatment News Nov 19 09"Results of US research 'challenge the notion that nevirapine is uniquely associated with hepatotoxicity during pregnancy.
Surviving to die of something else: AIDS is a rare cause of death in old people with HIV
AIDS Treatment News Nov 19 09"A French study of a group of people with HIV aged over 60 has found that over a four-year period, one in seven of the group died – but not a single death was attributable to an AIDS-defining illness.
Early Treatment, Non-AIDS Disease Management Stressed in New European Guidelines
AIDS Treatment News Nov 19 09"Antiretroviral (ARV) therapy is now recommended for certain people living with HIV with CD4 counts between 350 and 500 cells, according to new HIV treatment guidelines released this week by the European AIDS Clinical Society (EACS).
Low Vitamin D Levels in Alpine HIV Study
AIDS Treatment News Nov 19 09"A new study adds to the evidence that vitamin D deficiency is common in people living with HIV. The new data, from an Italian study reported last week at the 12th European AIDS Conference in Cologne, Germany, and summarized by the National AIDS Treatment Advocacy Project (NATAP), underscore the potential importance of testing for and treating low vitamin D levels to thwart the increased risk of bone deterioration and immune system dysfunction in those infected with the virus.
Protease inhibitor monotherapy as a maintenance regimen: are we edging towards acceptance?
AIDS Treatment News Nov 19 09"An entire session at the 12th European AIDS Conference was devoted to trials of different ritonavir-boosted protease inhibitors (PI/r) used as the sole drug in an antiretroviral regimen.
November 23: New deadline to submit ideas for the National AIDS Strategy
AIDS Treatment News Nov 16 09"1. Brainstorm ideas and identify specific action steps that address the three National HIV/AIDS Strategy goals to reduce HIV incidence, increase access to care and optimize health outcomes for people living with HIV, and reduce HIV-related health disparities.
Higher Viral Loads Associated With Metabolic Syndrome
AIDS Treatment News Nov 14 09"People with higher HIV levels are more likely to have a cluster of symptoms—called metabolic syndrome—associated with cardiovascular disease than people with lower viral loads, according to a study published in the December [2009] issue of the Journal of Acquired Immune Deficiency Syndromes.
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